{"id":10358,"date":"2026-06-20T05:43:24","date_gmt":"2026-06-20T05:43:24","guid":{"rendered":"https:\/\/nephizlabs.com\/epithalon-2\/"},"modified":"2026-08-11T02:15:08","modified_gmt":"2026-08-11T02:15:08","slug":"epithalon","status":"publish","type":"page","link":"https:\/\/nephizlabs.com\/cs\/epithalon\/","title":{"rendered":"EPITHALON"},"content":{"rendered":"\t\t
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Dom\u016f<\/a> > Znalosti<\/a> > V\u00fdzkumn\u00e1 knihovna<\/a> > EPITHALON<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t

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EPITHALON<\/h1>\t\t\t\t<\/div>\n\t\t\t\t
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V\u00ddZKUMN\u00dd PR\u016eVODCE<\/h3>\t\t\t\t<\/div>\n\t\t\t\t
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EPITHALON je syntetick\u00fd tetrapeptid, kter\u00fd byl zkoum\u00e1n v bun\u011b\u010dn\u00fdch kultur\u00e1ch a zv\u00ed\u0159ec\u00edch modelech s ohledem na aktivitu telomer\u00e1zy, d\u00e9lku telomer a biomarkery souvisej\u00edc\u00ed s v\u011bkem.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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\"\"<\/figure>

01. CO JE EPITHALON?<\/span><\/h3>

EPITHALON je syntetick\u00fd tetrapeptid (Ala-Glu-Asp-Gly). Publikovan\u00e9 studie zkoumaly aktivitu telomer\u00e1zy a d\u00e9lku telomer v bun\u011b\u010dn\u00fdch kultur\u00e1ch a koncov\u00e9 body souvisej\u00edc\u00ed s v\u011bkem u my\u0161\u00ed. Tyto v\u00fdsledky neprokazuj\u00ed \u00fa\u010dinky proti st\u00e1rnut\u00ed nebo dlouhov\u011bkost u lid\u00ed.

Tento pr\u016fvodce slou\u017e\u00ed v\u00fdhradn\u011b pro vzd\u011bl\u00e1vac\u00ed a v\u00fdzkumn\u00e9 \u00fa\u010dely.<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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02. OBLASTI V\u00ddZKUMU<\/span><\/h5>\t\t\t\t<\/div>\n\t\t
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\"\"<\/figure>

V\u00fdzkum telomer<\/h3>

Bun\u011b\u010dn\u00e9 a zv\u00ed\u0159ec\u00ed studie d\u00e9lky telomer, aktivity telomer\u00e1zy a chromozom\u00e1ln\u00ed stability.<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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\"\"<\/figure>

Modely bun\u011b\u010dn\u00e9ho st\u00e1rnut\u00ed<\/h3>

V\u00fdzkum bun\u011b\u010dn\u00e9ho st\u00e1rnut\u00ed a prolifera\u010dn\u00ed \u017eivotnosti bun\u011b\u010dn\u00fdch populac\u00ed.<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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\"\"<\/figure>

Koncov\u00e9 body souvisej\u00edc\u00ed s imunitou<\/h3>

Preklinick\u00e9 studie imunitn\u00edch a v\u011bkem souvisej\u00edc\u00edch koncov\u00fdch bod\u016f.<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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\"\"<\/figure>

Omezen\u00ed d\u016fkaz\u016f<\/h3>

Neexistuj\u00ed \u017e\u00e1dn\u00e9 spolehliv\u00e9 klinick\u00e9 d\u016fkazy pro vitalitu, vytrvalost nebo celkovou pohodu u lid\u00ed.<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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03. P\u0158EHLED V\u00ddZKUMU<\/span><\/h5>\t\t\t\t<\/div>\n\t\t\t\t
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\r\n\r\n
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<\/div>\r\n\r\n
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1<\/div>\r\n
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\r\n \"Epithalon\r\n <\/div>\r\n
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EPITHALON ve v\u00fdzkumn\u00fdch modelech<\/h3>\r\n

Zkoum\u00e1n\u00ed v bun\u011b\u010dn\u00fdch kultur\u00e1ch a zv\u00ed\u0159ec\u00edch modelech; \u017e\u00e1dn\u00e9 pokyny k pou\u017eit\u00ed.<\/p>\r\n <\/div>\r\n <\/div>\r\n <\/div>\r\n\r\n

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2<\/div>\r\n
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\r\n \"Untersuchung\r\n <\/div>\r\n
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Zkoum\u00e1n\u00ed v bun\u011b\u010dn\u00fdch modelech<\/h3>\r\n

Experiment\u00e1ln\u00ed studie zkoumaj\u00ed bun\u011b\u010dn\u00e9 reakce na EPITHALON.<\/p>\r\n <\/div>\r\n <\/div>\r\n <\/div>\r\n\r\n

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3<\/div>\r\n
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\r\n \"Telomerasebezogene\r\n <\/div>\r\n
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Aktivita souvisej\u00edc\u00ed s telomer\u00e1zou<\/h3>\r\n

V bun\u011b\u010dn\u00fdch kultur\u00e1ch byla zkoum\u00e1na aktivita telomer\u00e1zy a d\u00e9lka telomer.<\/p>\r\n <\/div>\r\n <\/div>\r\n <\/div>\r\n\r\n

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4<\/div>\r\n
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\r\n \"Grenzen\r\n <\/div>\r\n
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Koncov\u00e9 body souvisej\u00edc\u00ed s telomerami<\/h3>\r\n

Byla m\u011b\u0159ena exprese hTERT, aktivita telomer\u00e1zy a d\u00e9lka telomer.<\/p>\r\n <\/div>\r\n <\/div>\r\n <\/div>\r\n

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5<\/div>\r\n
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\r\n \"Grenzen\r\n <\/div>\r\n
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Omezen\u00ed d\u016fkaz\u016f<\/h3>\r\n

Bun\u011b\u010dn\u00e1 a zv\u00ed\u0159ec\u00ed data neprokazuj\u00ed \u00fa\u010dinek u lid\u00ed.<\/p>\r\n <\/div>\r\n <\/div>\r\n <\/div>\r\n\r\n <\/div>\r\n<\/div>\r\n\r\n