{"id":11444,"date":"2026-06-15T06:55:51","date_gmt":"2026-06-15T06:55:51","guid":{"rendered":"https:\/\/nephizlabs.com\/nad-2\/"},"modified":"2026-08-11T04:12:57","modified_gmt":"2026-08-11T04:12:57","slug":"nad","status":"publish","type":"page","link":"https:\/\/nephizlabs.com\/tr\/nad\/","title":{"rendered":"NAD+"},"content":{"rendered":"\t\t
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Ana Sayfa<\/a> > Bilgi<\/a> > Ara\u015ft\u0131rma K\u00fct\u00fcphanesi<\/a> > NAD+<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t

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NAD+<\/h1>\t\t\t\t<\/div>\n\t\t\t\t
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ARA\u015eTIRMA KILAVUZU<\/h3>\t\t\t\t<\/div>\n\t\t\t\t
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NAD+ (Nikotinamid adenin din\u00fckleotit), her h\u00fccrede bulunan bir koenzimdir ve h\u00fccresel enerji \u00fcretimi, DNA onar\u0131m\u0131, metabolizma ve sa\u011fl\u0131kl\u0131 ya\u015flanma i\u00e7in gereklidir.
her h\u00fccrede bulunan bir koenzimdir ve h\u00fccresel enerji \u00fcretimi, DNA onar\u0131m\u0131, metabolizma ve sa\u011fl\u0131kl\u0131 ya\u015flanma i\u00e7in gereklidir.
h\u00fccresel enerji \u00fcretimi, DNA onar\u0131m\u0131, metabolizma
ve sa\u011fl\u0131kl\u0131 ya\u015flanma.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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01. NAD+ NED\u0130R?<\/span><\/h3>

NAD+, besinleri enerjiye d\u00f6n\u00fc\u015ft\u00fcren redoks reaksiyonlar\u0131nda yer alan hayati bir koenzimdir. Ayr\u0131ca DNA onar\u0131m\u0131n\u0131, gen ifadesini ve h\u00fccre sa\u011fl\u0131\u011f\u0131n\u0131 d\u00fczenleyen sirtuinler ve PARP'lar gibi enzimler i\u00e7in bir substrat g\u00f6revi g\u00f6r\u00fcr.

Bu k\u0131lavuz yaln\u0131zca e\u011fitim ve ara\u015ft\u0131rma ama\u00e7l\u0131d\u0131r.<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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02. ARA\u015eTIRMA ALANLARI<\/span><\/h5>\t\t\t\t<\/div>\n\t\t
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\"\"<\/figure>

H\u00fccresel Enerji<\/h3>

H\u00fccresel enerji temini i\u00e7in mitokondriyal fonksiyonu ve ATP \u00fcretimini destekler.<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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DNA Onar\u0131m\u0131<\/h3>

DNA onar\u0131m\u0131 ve genomik kararl\u0131l\u0131kta \u00f6nemli rol oynayan PARP'lar i\u00e7in substrat g\u00f6revi g\u00f6r\u00fcr.<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Sa\u011fl\u0131kl\u0131 Ya\u015flanma<\/h3>

Uzun \u00f6m\u00fcr sinyal yollar\u0131n\u0131 destekleyen ve h\u00fccre sa\u011fl\u0131\u011f\u0131n\u0131n korunmas\u0131na katk\u0131da bulunan sirtuinleri aktive eder.<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Metabolik Fonksiyon<\/h3>

Glikoz metabolizmas\u0131 ve lipit d\u00f6ng\u00fcs\u00fc dahil olmak \u00fczere temel metabolik yollarda yer al\u0131r.<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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03. MEKAN\u0130ZMA \u00d6ZET\u0130<\/span><\/h5>\t\t\t\t<\/div>\n\t\t\t\t
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\r\n\r\n
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<\/div>\r\n\r\n
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1<\/div>\r\n
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\r\n \"NAD+\"\r\n <\/div>\r\n
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NAD+ Takviyesi<\/h3>\r\n

NAD+ seviyelerini desteklemek i\u00e7in ara\u015ft\u0131rma ama\u00e7l\u0131 stabil formda sa\u011flan\u0131r.<\/p>\r\n <\/div>\r\n <\/div>\r\n <\/div>\r\n\r\n

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2<\/div>\r\n
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\r\n \"Sirtuin-Aktivierung\"\r\n <\/div>\r\n
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Sirtuin Aktivasyonu\r\n<\/h3>\r\n

NAD+, uzun \u00f6m\u00fcr ve stres direnci ile ili\u015fkili genleri d\u00fczenleyen sirtuinleri aktive eder.<\/p>\r\n <\/div>\r\n <\/div>\r\n <\/div>\r\n\r\n

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3<\/div>\r\n
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\r\n \"DNA-Reparatur\"\r\n <\/div>\r\n
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DNA Onar\u0131m Deste\u011fi<\/h3>\r\n

NAD+, DNA hasar\u0131n\u0131n onar\u0131m\u0131 i\u00e7in gerekli olan PARP enzimleri i\u00e7in bir substratt\u0131r.<\/p>\r\n <\/div>\r\n <\/div>\r\n <\/div>\r\n\r\n

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4<\/div>\r\n
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\r\n \"Stoffwechsel\"\r\n <\/div>\r\n
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Mitokondriyal Destek<\/h3>\r\n

Mitokondriyal fonksiyonu ve h\u00fccresel enerji \u00fcretim verimlili\u011fini art\u0131r\u0131r.<\/p>\r\n <\/div>\r\n <\/div>\r\n <\/div>\r\n

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5<\/div>\r\n
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\r\n \"Stoffwechsel\"\r\n <\/div>\r\n
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Olas\u0131 Etkiler\r\n<\/h3>\r\n

Sa\u011fl\u0131kl\u0131 ya\u015flanmay\u0131, enerji dengesini, metabolizmay\u0131 ve genel h\u00fccre sa\u011fl\u0131\u011f\u0131n\u0131 destekleyebilir.<\/p>\r\n <\/div>\r\n <\/div>\r\n <\/div>\r\n\r\n <\/div>\r\n<\/div>\r\n\r\n