A mitochondrial-derived peptide studied for its role in metabolic regulation, insulin sensitivity, and cellular energy homeostasis in research models.
MOTS-c is a 16-amino-acid peptide encoded within the mitochondrial genome that has been investigated for its influence on cellular metabolism. Research models explore its association with AMPK pathway activation, glucose handling, and the regulation of nuclear gene expression under metabolic stress conditions.
In laboratory settings, MOTS-c is frequently studied in the context of exercise physiology, insulin signaling, and age-related metabolic decline, positioning it as a subject of interest in mitochondrial biology research.
Studied for its association with insulin sensitivity and glucose uptake in cellular research models.
Investigated for potential activation of AMPK, a key regulator of cellular energy balance.
Researched in the context of exercise capacity and skeletal muscle metabolic adaptation.
Examined for its role in mitochondrial biogenesis and nuclear-mitochondrial signaling communication.
Bring the vial (10 mg · 40 mg) and bacteriostatic water to room temperature.
Add bacteriostatic water slowly along the glass wall — the volume you add sets the concentration.
Swirl gently (do not shake) until fully clear, then refrigerate at 2–8 °C.
Studied together in research contexts exploring mitochondrial energy production and cellular metabolic pathways.
Investigated in parallel for complementary interest in metabolic and adipose-related research models.
Links open a PubMed search for the topic. They point to independent literature and are provided for orientation in a research context only.
MOTS-c is researched in the context of metabolic regulation, insulin sensitivity, and mitochondrial energy homeostasis. All investigation occurs within laboratory and preclinical research models, not clinical application.
It is a mitochondrial-derived peptide encoded within the mitochondrial genome. Research examines its potential signaling role between mitochondria and the nucleus during metabolic stress.
No. MOTS-c is supplied strictly for laboratory research purposes. It is not approved for human or veterinary use and carries no medical indications.

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