A non-erythropoietic peptide derived from erythropoietin, researched for tissue-protective and anti-inflammatory signalling via the innate repair receptor.
ARA-290, also called cibinetide, is an 11-amino-acid peptide modelling a region of erythropoietin that does not stimulate red-blood-cell production. Research focuses on its interaction with the innate repair receptor complex and downstream tissue-protective and anti-inflammatory effects.
Preclinical and exploratory studies examine neuropathic and inflammatory models. It remains an investigational research compound.
Studied in preclinical models of small-fibre neuropathy for nerve-protective signalling.
Researched for anti-inflammatory effects through the innate repair receptor pathway.
Examined for cytoprotective signalling without stimulating erythropoiesis.
Investigated in experimental models exploring tissue recovery and immune balance.
Bring the vial (10 mg) and bacteriostatic water to room temperature.
Add bacteriostatic water slowly along the glass wall — the volume you add sets the concentration.
Swirl gently (do not shake) until fully clear, then refrigerate at 2–8 °C.
Paired in repair research combining receptor-mediated protection with angiogenic signalling.
Studied together for complementary immune-modulating and tissue-protective mechanisms.
Links open a PubMed search for the topic. They point to independent literature and are provided for orientation in a research context only.
It models a non-erythropoietic region of EPO, so research indicates it engages tissue-protective receptor pathways without stimulating red-blood-cell production, allowing study of protective effects in isolation.
It is a receptor complex researched as the target for ARA-290's tissue-protective and anti-inflammatory signalling, distinct from the classical erythropoietin receptor.
Exploratory research has focused on neuropathic and inflammatory models. It remains a research-only investigational compound with no approved therapeutic use.
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