A naturally occurring copper-binding tripeptide researched for its roles in skin remodelling, collagen synthesis, and antioxidant signalling.
GHK-Cu is a complex of the tripeptide glycyl-L-histidyl-L-lysine bound to copper. It occurs naturally in plasma and declines with age. Research examines its influence on collagen and glycosaminoglycan production, matrix remodelling, and modulation of gene expression related to tissue repair.
It is studied extensively in dermatological and wound-model contexts as well as in gene-regulation research. GHK-Cu is used only as a research and cosmetic-science reagent.
Studied for stimulating collagen and glycosaminoglycan production in dermal fibroblast models.
Researched for broad modulation of genes involved in tissue remodelling and repair.
Examined for scavenging of reactive species and protection of skin cells in vitro.
Investigated for matrix reorganisation and reduced scarring in experimental wound models.
Bring the vial (50 mg) and bacteriostatic water to room temperature.
Add bacteriostatic water slowly along the glass wall — the volume you add sets the concentration.
Swirl gently (do not shake) until fully clear, then refrigerate at 2–8 °C.
Paired in dermal-repair research combining copper remodelling with actin-driven migration.
Studied together for complementary matrix-remodelling and angiogenic repair signalling.
Links open a PubMed search for the topic. They point to independent literature and are provided for orientation in a research context only.
It is a copper-bound tripeptide occurring naturally in human plasma, researched for its effects on collagen production, tissue remodelling, and gene expression in laboratory and cosmetic-science models.
The peptide's high affinity for copper is central to its studied biology; the copper complex is thought to mediate many of the remodelling and antioxidant effects observed in research.
It is usually provided as a lyophilised blue powder in 50 mg vials for reconstitution in research and cosmetic-formulation studies.
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